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The Colon As A Serious Website Of Immunoregulation By Cd4+ T Cell Subsets In The Regular State However, only in the pyloric caeca region, IgM transcription was significantly higher in vaccinated fish than in management groups (Fig. 4A). In the case of IgT and IgD transcription, once more, solely within the pyloric caeca area the values obtained in the vaccinated group have been considerably larger than these obtained within the management teams (Fig. 4B and 4C). Given that both Blimp1 and Pax5 transcription levels had been up-regulated in response to oral vaccination in the pyloric caeca, regardless of being a priori negatively correlated, we decided to additional examine the transcription of those components. For this, the degrees of transcription of Blimp1 and Pax5 in the different gut segments have been studied in perfused blood-depleted naïve fish, evaluating them to the degrees observed in PBLs. As already observed in the vaccination trial, Blimp1 was not considerably transcrib

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